What change in adrenal hormone levels can lead to symptoms such as fatigue and poor wound healing?

The presence of excess glucocorticoids in the body can lead to a range of symptoms, including fatigue and poor wound healing. Glucocorticoids, primarily cortisol, play a significant role in regulating metabolism, immune responses, and stress responses. When these hormones are produced in excess, as seen in conditions like Cushing's syndrome, they can disrupt normal physiological functions.

Sustained high levels of glucocorticoids can contribute to muscle weakness, fatigue, and impaired immune function, making it harder for the body to heal wounds effectively. This occurs due to their catabolic effects on muscle and tissues, as well as their ability to suppress the inflammatory response that is crucial for effective wound healing. Additionally, excess glucocorticoids can lead to other complications such as increased blood sugar levels and altered fat distribution, both of which can further exacerbate feelings of fatigue and lead to poor healing outcomes.

Other hormone levels, such as decreased mineralocorticoids or increased catecholamines, have different paths of influence on the body and are not directly linked to the specific symptoms of fatigue and wound healing in the same way that excess glucocorticoids are. Similarly, low thyroid hormones impact metabolism but do not directly correlate to