What complication is associated with untreated Diabetes Insipidus?

The complication associated with untreated Diabetes Insipidus that aligns with the context of the question is circulatory collapse. Diabetes Insipidus is characterized by an inadequate secretion of the anti-diuretic hormone (ADH), leading to significant water loss through the kidneys. This condition can result in severe dehydration due to the excessive urination (polyuria) and thirst (polydipsia) that are hallmarks of the disease.

As dehydration progresses, the body may lose a dangerous amount of fluid volume, which can lead to a state of hypovolemia. If the volume of circulating blood decreases significantly, this can result in circulatory collapse, where the heart cannot pump sufficient blood to meet the body's needs. Symptoms may include very low blood pressure, accelerated heart rate, and potentially shock if not treated promptly.

The other options, while they may have health implications in different contexts, are not direct complications stemming specifically from untreated Diabetes Insipidus. Osteoporosis, chronic kidney disease, and heart failure more closely relate to long-term metabolic imbalances or chronic disease states rather than the immediate physiological consequences of a lack of ADH.