Which of the following is NOT a symptom of Cushing Syndrome?

Cushing Syndrome is characterized by an excess of cortisol in the body, leading to a range of distinctive symptoms. One of the hallmark features of this condition is weight gain, particularly in specific areas such as the abdomen and face.

Weight loss, on the other hand, is not associated with Cushing Syndrome. Instead, individuals with this syndrome typically experience increases in body weight due to fat redistribution and fluid retention. Symptoms like moon face, buffalo hump, and ecchymosis are all related to changes in fat distribution and skin texture due to the effects of cortisol. Moon face refers to a rounded facial appearance, buffalo hump denotes fat accumulation between the shoulders, and ecchymosis involves the easy bruising seen in many patients due to skin changes and vascular fragility associated with prolonged cortisol elevation.

In conclusion, recognizing that weight loss is contrary to the typical presentation of Cushing Syndrome helps to distinguish it clearly from the other symptoms that are indicative of this endocrine disorder.